Spidey's only hope of stopping a world takeover is to team up with Nick Fury's secret team of super-powered monsters, The Howling Commandos. Led by Jack Russell, aka Werewolf by Night, The Howling Commandos include vampire hunter Blade, The Living Mummy, Frankenstein's Monster and Man-Thing.

The episode was rated 7.89 from 158 votes.

Spider-Man accepts an invitation from Boston to become the city's official hero.

The episode was rated 7.91 from 186 votes.

Doc Ock launches a surprise attack on Spider-Man and the heroes. They soon find themselves in one of the most challenging battles of the season when they're up against the newly reformed Sinister Six. Norman Osborn also returns as Iron Patriot despite Ock's alternate plans for him.

The episode was rated 7.94 from 144 votes.

The Green Goblin returns and tries to make Spider-Man into his perfect weapon, but Carnage has other ideas for the duo.

The episode was rated 7.96 from 184 votes.

Sandman proves he might not be the biggest bad after all. He's given the chance to start all over and Spidey must mentor his former foe as he struggles against his old instincts. What side will Sandman ultimately choose, hero or villain?

The episode was rated 7.97 from 142 votes.

Spider-Man and The Hulk switch minds, leading to lots of craziness and a clobberin’ from The Thing of The Fantastic Four.

The episode was rated 8.02 from 166 votes.

Mutant terrorist Arcade becomes one of S.H.I.E.L.D.'s biggest threats. Spidey must change all of the rules to defeat this cyber nemesis, but he can't do it alone. He teams up with Captain America and Wolverine to beat Arcade at his own game, but will it be enough before it's game over?

The episode was rated 8.03 from 159 votes.

Spider-Man fights alone against his own team to save all of New York from being turned into Green Goblins.

The episode was rated 8.04 from 157 votes.

Spider-Man, Mary Jane, Harry and Stan the Janitor have to descend into the sewer tunnels beneath Midtown High to track down the Lizard.

The episode was rated 8.04 from 181 votes.

Spider-Man forms an unlikely partnership with a cured Norman Osborn. But is Norman really a hero as the Iron Patriot?

The episode was rated 8.07 from 138 votes.

Spider-Man travels to the mystical city of K’un L’un to help Iron Fist fulfill his destiny. But The Scorpion plans to destroy them both.

The episode was rated 8.09 from 174 votes.

Spider-Man and Nova team up with The Guardian’s of the Galaxy on a deep space adventure to save Earth from destruction.

The episode was rated 8.11 from 160 votes.

Spider-Man and Power Man infiltrate Zodiac's base to discover what happened to Power Man's parents

The episode was rated 8.16 from 145 votes.

Spider-Man must work with his nemesis, Doctor Octopus, when The Green Goblin unleashes Venom on the Tricarrier.

The episode was rated 8.24 from 154 votes.

Deadpool returns to SHIELD to help find the accomplice that stole a list of secret identities, so Spider-Man joins him to track down Taskmaster.

The episode was rated 8.27 from 175 votes.