Michael Stewart Stuhlbarg (born July 5, 1968) is an American actor. He rose to prominence as troubled university professor Larry Gopnik in the 2009 dark comedy film A Serious Man, directed by Joel and Ethan Coen. Stuhlbarg has appeared in numerous films and television series portraying real life figures, such as George Yeaman in Lincoln (2012), Lew Wasserman in Hitchcock (2012), Andy Hertzfeld in Steve Jobs (2015), Edward G. Robinson in Trumbo (2015), Abe Rosenthal in The Post (2017), Stanley Edgar Hyman in Shirley (2020), Arnold Rothstein in HBO's Boardwalk Empire (2010–2013), Richard A. Clarke in The Looming Tower (2018), and as Richard Sackler in Dopesick (2021). His performance in The Looming Tower earned him a Primetime Emmy Award nomination for Outstanding Supporting Actor in a Limited Series or Movie. Stuhlbarg's other notable supporting roles include Hugo (2011), Men in Black 3 (2012), Blue Jasmine (2013), Pawn Sacrifice (2014), Arrival (2016), and Doctor Strange (2016), the third season of the anthology television series Fargo (2017), as well as on the Showtime series Your Honor (2020-present). In 2017, Stuhlbarg appeared in the films Call Me by Your Name, The Shape of Water, and The Post, all three of which were nominated for the Academy Award for Best Picture. For Call Me By Your Name, Stuhlbarg received multiple film critics' award nominations in the supporting actor category. On stage, Stuhlbarg has acted in numerous productions including the 2005 debut of The Pillowman on Broadway, for which he won a Drama Desk Award and received a Tony Award nomination.

Michael Stuhlbarg plays as Jimmy Baxter in Dopesick.
Michael Stuhlbarg is the top #1 member of the cast and appears in 13 episodes.

Rosario Isabel Dawson (born May 9, 1979) is an American actress, singer, and writer from New York City. She made her film debut in Kids (1995) and has also appeared in a number of films including Men in Black II (2002), The Rundown (2003), Alexander (2004), 25th Hour (2005), Sin City (2005), Rent (2005), Clerks II (2006), Death Proof (2007), Eagle Eye (2008), Seven Pounds (2008), Percy Jackson and the Olympians: The Lightning Thief (2010), Unstoppable (2010) and Top Five (2014). Dawson also portrays Claire Temple in the Marvel Cinematic Universe as part of five Marvel/Netflix shows: Daredevil, Jessica Jones, Luke Cage, Iron Fist, and The Defenders.

Rosario Dawson plays as Self - Judge in Dopesick.
Rosario Dawson is the top #2 member of the cast and appears in 13 episodes.

Kaitlyn Rochelle Dever (born December 21, 1996) is an American actress. She has appeared in several television series, including Justified (2011–2015) and Last Man Standing (2011–present), and starred in the Netflix miniseries Unbelievable (2019) for which she earned a Golden Globe Award nomination for Best Actress – Miniseries. In film, Dever has taken on supporting parts in Bad Teacher (2011), The Spectacular Now (2013), Short Term 12 (2013), Detroit (2017), and Beautiful Boy (2018). She has also played leading roles in the 2019 films Them That Follow and Booksmart.

Kaitlyn Dever plays as Betsy Mallum in Dopesick.
Kaitlyn Dever is the top #3 member of the cast and appears in 4 episodes.

John Hoogenakker is an actor.

John Hoogenakker plays as Randy Ramseyer in Dopesick.
John Hoogenakker is the top #4 member of the cast and appears in 4 episodes.

Michael John Douglas (born September 5, 1951), better known as Michael Keaton, is an American actor, well known for his early comedic roles in films such as Night Shift, Mr. Mom, Johnny Dangerously, Beetlejuice, and for his dramatic portrayal of Batman in Tim Burton's Batman and Batman Returns, as well as lead roles in other films including The Paper, Jackie Brown, Jack Frost, White Noise, Cars, The Other Guys and Toy Story 3.

Michael Keaton plays as Samuel Finnix in Dopesick.
Michael Keaton is the top #5 member of the cast and appears in 4 episodes.

English actor William Jack Poulter is most notable for his role as Gally in The Maze Runner, and as Kenny Rossmore in We're the Millers.

Will Poulter plays as Billy Cutler in Dopesick.
Will Poulter is the top #6 member of the cast and appears in 4 episodes.

John Peter Sarsgaard (born March 7, 1971) is an American actor. His first feature role was in Dead Man Walking in 1995. He then appeared in the 1998 independent films Another Day in Paradise and Desert Blue. That same year, Sarsgaard received a substantial role in The Man in the Iron Mask (1998), playing Raoul, the ill-fated son of Athos. Sarsgaard later achieved critical recognition when he was cast in Boys Don't Cry (1999) as John Lotter. He landed his first leading role in the 2001 film The Center of the World. The following year, he played supporting roles in Empire, The Salton Sea, and K-19: The Widowmaker. For his portrayal of Charles Lane in Shattered Glass, Sarsgaard won the National Society of Film Critics Award for Best Supporting Actor and was nominated for the 2004 Golden Globe Award for Best Supporting Actor. Sarsgaard has appeared in an eclectic range of films, including the 2004 comedy-drama Garden State, the biographical film Kinsey (2004), the drama The Dying Gaul (2005), and big-budget films such as Flightplan (2005), Jarhead (2005), The Skeleton Key (2005), Orphan (2009), An Education (2009), Knight and Day (2010), Green Lantern (2011), Lovelace (2013), Kelly Reichardt's Night Moves (2013), Blue Jasmine (2013), Black Mass (2015), and The Magnificent Seven (2016). Sarsgaard also appeared in the American TV series The Killing (2013) as a man on death row perhaps wrongfully convicted for the brutal murder of his wife—a performance which he says included "some of the best acting I have ever done in my life." In 2021, he had a recurring role on the Hulu miniseries Dopesick. Sarsgaard has appeared in Off-Broadway productions including Kingdom of Earth, Laura Dennis, Burn This, and Uncle Vanya. In September 2008, he made his Broadway debut as Boris Alexeyevich Trigorin in The Seagull. He is married to actress Maggie Gyllenhaal.

Peter Sarsgaard plays as Tommy Molto in Dopesick.
Peter Sarsgaard is the top #7 member of the cast and appears in 0 episodes.