Lewis, Neela, and Sam are legally blocked from treating a woman dying from the effects of a hunger strike designed to prevent her son from being deported. Pratt struggles to find a way to convince a woman with breast cancer to seek treatment. Abby treats two elderly sisters involved in a mugging. To Weaver's delight, Carter donates $150 million to the hospital's new venture, in exchange for naming rights. Carter calls Kem and asks her opinion on The Joshua Carter Center, named after their stillborn son.

The episode was rated 7.32 from 72 votes.

It is Neela's first day back at the ER and Pratt orders each intern to discharge 25 patients by the end of their shift, tracking their output. Neela struggles with frustration as she trails in the competition and is asked rude personal questions by a medical student Jane Figler while trying to help a patient with severe leukemia. Ray leads by a landslide, but makes a major mistake by green-lighting organ donation against the family's wishes after he sped through the paperwork. Not interested in the competition, Abby fakes a needle prick in order to get HIV-protective medication for a worried patient- and deals with a med student who is smitten for her. Dubenko looks out for Abby when Ray rides all over her in a trauma. Dubenko is also a little obsessed with physics.

The episode was rated 7.28 from 78 votes.

Neela has a recurring dream; Gates tries to save a patient who jumped out of a window while sleeping; Neela is surprised to see Dr. Corday.

The episode was rated 7.28 from 69 votes.

Morris tries to help a girl who was hit while riding her bike; Gates can't get over his feelings for Sam; Neela is flustered when Dr. Brenner returns from Australia.

The episode was rated 7.26 from 65 votes.

Gallant and Neela have been exchanging letters regularly. Gallant struggles with the war he sees every day, while Neela is searching for her life's purpose. Gallant enlists Neela's help in getting a critically burned Iraqi girl lined up for surgery in Chicago and heads for the U.S. with 72 hours leave.

The episode was rated 7.25 from 76 votes.

Susan receives a message from her niece on her answering machine, saying that Chloe's "sick." The call is traced to New York City, putting Susan on a plane. Officers Boscarelli and Yokas are assigned to chaperone Susan in the search for her sister. Chloe is found in "Urinetown," suffering a broken heart, but Little Suzie is not with her. Pratt hits on Chen several times throughout the day, and also performs an unauthorized procedure with Gallant on a dying man. Abby returns to her apartment, where Carter catches her drinking a beer. He confronts Luka about her relapse, and Abby herself later. She tells Carter not to worry about her. Romano signs Weaver up to meet with the Women's Health Coalition. Corday requests immediate time off from Romano to join Mark and Rachel in Hawaii. (Unleashed (2) aired on Third Watch, season 3, episode 19.)

The episode was rated 7.24 from 99 votes.

A frantic Sam and Luka report diabetic Alex missing after he runs away to find his father. Acting on information from the police, they follow a lead to Iowa, then eventually head for Colorado. As they travel, they discuss their relationship, Sam tells Luka she doesn't want anymore kids. After finding Alex safe, Sam tells him the truth and takes him to see his father. In the ER, Susan, Pratt, and the nurses evaluate Ray, Neela, and Abby’s first days as R2s, while each of them struggle to manage patients, new interns, and their first attempts at teaching.

The episode was rated 7.19 from 79 votes.

In the wake of heavy rains, the ER is flooded with diverse patients, including a baby involved in a suspicious car crash with her mother and a heart-attack victim visited by his sex therapist. Sam confronts Eve about her strict ways. Abby learns the details of Dubenko's condition and tactfully refuses his advances. Kovač protests when nursing home workers drop off Blaire Collins, who has been comatose for six years, for routine care, but later in the day, she unexpectedly regains consciousness.

The episode was rated 7.16 from 81 votes.

Dr. Banfield is irritated when Morris takes Chaz under his wing and teaches him risky medical procedures; Neela is unhappy when Dr. Banfield undermines her authority with an intern.

The episode was rated 7.16 from 63 votes.

Alex is set to be released from the hospital. Doctors treat African-American brothers Curtis Bennet, 17, who has abdominal pain and 10-year-old Quincy Bennet who has a knee injury. Both were injured during a drug deal that went terribly wrong. There's still some residual tension between Gates and Sam. A female patient in police custody doesn't want to be examed by Morris. A 13-year-old patient named Anastasia messes with Neela's love life.

The episode was rated 7.16 from 64 votes.