Leila Kenzle plays as Fran Devanow in Mad About You.
Leila Kenzle is the top #1 member of the cast and appears in 142 episodes.

​From Wikipedia, the free encyclopedia John Pankow (born April 28, 1954) is an American film and stage actor. He is perhaps best known for a supporting role on the sitcom Mad About You (1993-1999). Description above from the Wikipedia article John Pankow, licensed under CC-BY-SA, full list of contributors on Wikipedia.

John Pankow plays as Ira Buchman in Mad About You.
John Pankow is the top #2 member of the cast and appears in 142 episodes.

Anne Ramsay is an American stage, film and television actress, writer and director, best known for playing Lisa Stemple on the television comedy show "Mad About You". She holds a BA in Theater from the University of California, Los Angeles, USA.

Anne Ramsay plays as Lisa Stemple in Mad About You.
Anne Ramsay is the top #3 member of the cast and appears in 119 episodes.

Lisa Valerie Kudrow-Stern is an American actress, best known for her role as Phoebe Buffay in the television sitcom Friends, for which she received many accolades including an Emmy Award and two Screen Actors Guild Awards. While starring in Friends, Kudrow also appeared in 1999's comedy film Analyze This, directed by Harold Ramis, as well as its 2002 sequel Analyze That. Kudrow has also appeared in several comedy films, notably playing Michele Weinberger in Romy and Michele's High School Reunion, and after Friends had ended, Kudrow featured in the 2009 feature film Bandslam as the character Karen Burton. She has also appeared in the comedies P.S. I Love You and Hotel For Dogs. On May 27, 1995, Kudrow became the first "Friend" to marry when she wed Michel Stern, a French advertising executive. They have one son, Julian Murray (born May 7, 1998), and live near Beverly Hills, California.  Kudrow's pregnancy was written into Friends with her character Phoebe having triplets as a surrogate parent for her brother and his wife because they were not able to have children. Description above from the Wikipedia article Lisa Kudrow, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Lisa Kudrow plays as Ursula Buffay in Mad About You.
Lisa Kudrow is the top #4 member of the cast and appears in 49 episodes.

From Wikipedia, the free encyclopedia Paul Reiser (born March 30, 1956) is an American actor, comedian, television writer, and musician. He is known for his roles as Michael Taylor in the 1980s sitcom My Two Dads, Paul Buchman in the NBC sitcom Mad About You, Modell in the 1982 film Diner, Carter Burke in the 1986 film Aliens, as Detective Jeffrey Friedman in Beverly Hills Cop (1984) and Beverly Hills Cop II (1987). More recently, Reiser is recognized as Jim Neiman in the 2014 film Whiplash and Doug Getty in the Amazon Video series Red Oaks. Description above from the Wikipedia article Paul Reiser, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Paul Reiser plays as Sam Owens in Mad About You.
Paul Reiser is the top #5 member of the cast and appears in 18 episodes.

From Wikipedia, the free encyclopedia. Helen Elizabeth Hunt (born June 15, 1963) is an American actress, film director, and screenwriter. She starred in the sitcom Mad About You for seven years, before being cast in the romantic comedy As Good as It Gets (for which she won the Academy Award for Best Actress) and The Curse of the Jade Scorpion. Some of her other Hollywood credits include Twister, Cast Away, What Women Want and Pay It Forward. She made her directorial debut in 2007 with Then She Found Me. Description above from the Wikipedia article Helen Hunt, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Helen Hunt plays as Rainey in Mad About You.
Helen Hunt is the top #6 member of the cast and appears in 8 episodes.