Juliet Rylance was born on July 26, 1979 in Hammersmith, London, England as Juliet Katherine Van Kampen. She is an actress and producer, known for The Knick (2014), A Dog's Purpose (2017) and Frances Ha (2012). She has been married to Christian Camargo since November 10, 2008.

Juliet Rylance plays as Della Street in Perry Mason.
Juliet Rylance is the top #1 member of the cast and appears in 8 episodes.

Franklin Shea Whigham Jr. (born January 5, 1969) is an American actor. He portrayed Elias "Eli" Thompson in the HBO drama series Boardwalk Empire, and had notable supporting roles in films Kong: Skull Island, Death Note, Take Shelter, and the first season of True Detective, the third season of Fargo, and Joker. He appeared as Agent Michael Stasiak in Fast & Furious and Fast & Furious 6. In 2020 he was cast as Pete Strickland on HBO's reimagining of Perry Mason, a role for which he received attention for his moustache. Description above from the Wikipedia article Shea Whigham, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Shea Whigham plays as Pete Strickland in Perry Mason.
Shea Whigham is the top #2 member of the cast and appears in 8 episodes.

Matthew Rhys Evans, known professionally as Matthew Rhys, is a Welsh actor, best-known as Kevin Walker on the U.S. ABC family drama "Brothers & Sisters", and as Dylan Thomas in "The Edge of Love".

Matthew Rhys plays as Perry Mason in Perry Mason.
Matthew Rhys is the top #3 member of the cast and appears in 8 episodes.

Chris Chalk is an American stage and screen actor, a graduate of the Theater Program at The University of North Carolina at Greensboro.

Chris Chalk plays as Paul Drake in Perry Mason.
Chris Chalk is the top #4 member of the cast and appears in 8 episodes.

Tatiana Gabriele Maslany (born September 22, 1985) is a Canadian actress. She rose to prominence for playing multiple characters in the science fiction thriller television series Orphan Black (2013–2017), which won her a Primetime Emmy Award (2016), two Critics' Choice Awards (2013 and 2014), and five Canadian Screen Awards (2014–18). Maslany is the first Canadian to win an Emmy in a major dramatic category for acting in a Canadian series. Maslany also appeared in television series such as Heartland (2008–2010), The Nativity (2010), Being Erica (2009–2011), Perry Mason (2020), and She-Hulk: Attorney at Law (2022) in the lead role of Jennifer Walters / She-Hulk. Her other notable films include Diary of the Dead (2007), Eastern Promises (2007), The Vow (2012), Picture Day (2012), Cas and Dylan (2013), Woman in Gold (2015), Stronger (2017), and Destroyer (2018). For starring in the romantic drama The Other Half (2016), she won the Canadian Screen Award for Best Actress.

Tatiana Maslany plays as Sister Alice McKeegan in Perry Mason.
Tatiana Maslany is the top #5 member of the cast and appears in 8 episodes.

John Arthur Lithgow (born October 19, 1945) is an American actor. Prolific in films, television and on stage, Lithgow is the recipient of numerous accolades, including two Golden Globe Awards, six Primetime Emmy Awards, three Screen Actors Guild Awards, two Tony Awards and nominations for two Academy Awards and four Grammy Awards. He was inducted into the American Theater Hall of Fame and has received a star on the Hollywood Walk of Fame. Lithgow studied at Harvard University winning a Fulbright scholarship and getting a chance to attend the London Academy of Music and Dramatic Art. From there he focused his training on the New York stage beginning a distinguished career on Broadway. In 1973, Lithgow received his first Tony Award for his performance in The Changing Room. In 1976 Lithgow acted alongside Meryl Streep in three plays 27 Wagons Full of Cotton, A Memory of Two Mondays and Secret Service. In the 1980s he continued to receive Tony Awards nominations for his performances in Requiem for a Heavyweight (1985) and M. Butterfly (1988). In 2002, Lithgow received his second Tony Award, this time for a musical, The Sweet Smell of Success and another nomination for Dirty Rotten Scoundrels (2005). In 2007, he made his Royal Shakespeare Company debut as Malvolio in Neil Bartlett's production of Twelfth Night. He has also appeared on Broadway in the acclaimed plays The Columnist (2012) and A Delicate Balance (2014). He portrayed Bill Clinton in Hillary and Clinton (2019) alongside Laurie Metcalf as Hillary Clinton. Lithgow is also known for his television roles such as Dick Solomon in the sitcom 3rd Rock from the Sun (1996–2001) winning three Primetime Emmy Awards for Best Actor in a Comedy Series for his performance. He also played Arthur Mitchell in the drama Dexter (2009) and he won the Primetime Emmy Award for Outstanding Guest Actor in a Drama. In 2004, Lithgow played Blake Edwards in the HBO television movie, The Life and Death of Peter Sellers. He has also appeared on 30 Rock, How I Met Your Mother, Louie and Drunk History. Lithgow won great acclaim for his portrayal of Winston Churchill in Peter Morgan's historical drama The Crown (2016–2019) on Netflix. For acting in The Crown he won a Primetime Emmy Award and Screen Actors Guild Award. In 2020, he had a recurring role on the HBO period series Perry Mason. He is also well known for his film roles. His early screen roles included Bob Fosse's All That Jazz (1979) and Brian De Palma's Blow Out (1981). He received his first Academy Award nomination for his breakout performance in The World According to Garp (1982) and received a second Academy Award nomination for Terms of Endearment (1983). He then starred in the films Footloose (1984), Harry and the Hendersons (1987), The Pelican Brief and Cliffhanger (1993), A Civil Action (1998), Rugrats in Paris: The Movie (2000), Shrek (2001), Kinsey (2004), Dreamgirls (2006), Love Is Strange (2014), Miss Sloane (2016) and Beatriz at Dinner (2017). In 2019 he appeared in Mindy Kaling's comedy Late Night and portrayed Roger Ailes in Bombshell. Description above from the Wikipedia article John Lithgow, licensed under CC-BY-SA, full list of contributors on Wikipedia.

John Lithgow plays as Harold Harper in Perry Mason.
John Lithgow is the top #6 member of the cast and appears in 7 episodes.