Nobuhiko Okamoto is a Japanese voice actor and singer from Tokyo, Japan, affiliated with Raccoon Dog. Previously, he was affiliated with the Pro-Fit agency. He won the Best New Actor Award on Third Seiyu Awards and Best Supporting Actor Award on Fifth Seiyu Awards.

Nobuhiko Okamoto plays as Yuu Nishinoya (voice) in Re:ZERO -Starting Life in Another World-.
Nobuhiko Okamoto is the top #1 member of the cast and appears in 85 episodes.

Kaori Nazuka is a Japanese freelance voice actress. She usually plays her characters with a signature childlike yet low-and-dignified voice. Nicknamed "Mr. duck". Major appearances are “ .hack // Roots ” (Shino), “ Symphonic Psalm Eureka Seven ” (Eureka), “ Gag Manga Days ” series, “ Silver Olinsis ” (Thea), “ Code Geass Lelouch of the Rebellion ” series (Nanally Lamperouge) etc.

Kaori Nazuka plays as Kiyoko Shimizu (voice) in Re:ZERO -Starting Life in Another World-.
Kaori Nazuka is the top #2 member of the cast and appears in 85 episodes.

Takehito Koyasu is a Japanese voice actor. Koyasu is part of the voice actor quartet Weiß consisting of Weiß Kreuz voice castmates Shinichiro Miki, Tomokazu Seki, and Hiro Yūki. He used to work for Production Baobab but is now the head of T's Factory, a voice actor company he founded in 1998. Koyasu is known for his deep, smooth voice, which often lands him in roles that are either villains or lonely bishōnen. Recently, though (as in the cases of Mitsurugi Hanagata from Saber Marionette J, Ryo Kuroyanagi from Yakitate!! Japan, Bobobo-bo Bo-bobo, and Kei Itoshiki from (Zoku) Sayonara, Zetsubou-Sensei) he has been voicing more and more lively/humorous characters. According to Hisaya Nakajo, the manga artist of the series Hana-Kimi, the character of Masao Himejima was designed with Koyasu's voice in mind; the voice actor ended up voicing this character in the series' drama CDs. On 18 September 2009, he created Velvet Underworld series which is the first drama CD of the series, "The Fool". In the following month, "The Wheel of Fortune" had released as the second drama CD of the series.

Takehito Koyasu plays as Dio Brando (voice), DIO (voice) in Re:ZERO -Starting Life in Another World-.
Takehito Koyasu is the top #3 member of the cast and appears in 74 episodes.

Maaya Sakamoto is a Japanese voice actress and singer. She made her debut as a voice actress in 1992 as the voice of Chifuru in Little Twins, but is better known as voice of Hitomi Kanzaki in The Vision of Escaflowne. Other major roles in anime include Riho Yamazaki in Nightwalker: The Midnight Detective, Moe Katsuragi in Risky Safety, Princess Tomoyo in Tsubasa Reservoir Chronicle, Haruhi Fujioka in Ouran High School Host Club, Sayaka Nakasugi in Birdy the Mighty, Ciel Phantomhive in Black Butler, Shinobu Oshino in Monogatari, Shiki Ryougi in the Kara no Kyoukai film series, and Motoko Kusanagi in the newer Ghost in the Shell films and series. In video games she voices Aura and Natsume in .hack, Lisa Hamilton / La Mariposa in Dead or Alive, Aeris in Kingdom Hearts, Aigis in Persona 3, Lightning in Final Fantasy XIII games, Ling Xiaoyu in the Tekken series, and Alisa Illinichina Amiella in God Eater. She has also branched into singing, performing songs in both English and Japanese. She released her debut single "Yakusoku wa Iranai" in collaboration with Yoko Kanno under Victor Entertainment on April 24, 1996. Her singles "Tune the Rainbow", "Loop", "Ame ga Furu", and "Triangler" have all reached the top 10 Oricon singles chart: "Triangler" in particular charted at number 3 and remained charting for 26 weeks. Her albums have had similar success, with Shōnen Alice and Yūnagi Loop both reaching the top 10 Oricon albums chart; and her album You Can't Catch Me, released on January 12, 2011, became her first release to ever reach number 1. She held a concert at the Nippon Budokan on March 31, 2010, her thirtieth birthday. In the Japanese localization of overseas dubs, she has voiced Padme Amidala as presented in the Star Wars films and cartoons, as well as being the dub voice for Natalie Portman on numerous films.

Maaya Sakamoto plays as Zero (voice) in Re:ZERO -Starting Life in Another World-.
Maaya Sakamoto is the top #4 member of the cast and appears in 48 episodes.

Yusuke Kobayashi is a Japanese voice actor. He is affiliated with Yu-rin Pro. In 2017, he won the Best New Actor Award at the 11th Seiyu Awards. He was born in Tokyo, and is 1.64 m tall.

Yusuke Kobayashi plays as Arthur Boyle (voice) in Re:ZERO -Starting Life in Another World-.
Yusuke Kobayashi is the top #5 member of the cast and appears in 48 episodes.

Inori Minase is a Japanese actress, voice actress and singer who made her singing debut in December 2015 under King Records label. In March 2016, she won the Best Lead Actress Award in the 10th Seiyu Awards for her leading roles as Jun Naruse in the box office hit The Anthem of the Heart and as Yuki Takeya in the anime television series School-Live!. Her other major roles include Chino in Is the Order a Rabbit?, Noel in Celestial Method, Hestia in Is It Wrong to Try to Pick Up Girls in a Dungeon?, Rem in Re:Zero − Starting Life in Another World, Chito in Girls' Last Tour, and Tamaki “Kimari” Mari in A Place Further than the Universe.

Inori Minase plays as Mabushiina (voice) in Re:ZERO -Starting Life in Another World-.
Inori Minase is the top #6 member of the cast and appears in 45 episodes.

** Not to be confused with Yuichi Nakamura (actor). They share the same name, but have different Kanji. ** Yuichi Nakamura is a Japanese voice actor. Previously affiliated with Sigma Seven and currently with Intention. He voiced Gray Fullbuster in Fairy Tail, Gai Tsutsugami in Guilty Crown, Tatsuya Shiba in The Irregular at Magic High School, Karamatsu in Osomatsu-san, Alto Saotome in Macross Frontier, Tomoya Okazaki in Clannad, Kyōsuke Kōsaka in Oreimo, Hotaro Oreki in Hyouka and Bruno Bucciarati in JoJo's Bizarre Adventure: Golden Wind. On video games, he voiced Hazama and Yūki Terumi in BlazBlue, Sakon Shima in Sengoku Basara 4, Cid Raines in Final Fantasy XIII, and Fei Long in Street Fighter IV.

Yuichi Nakamura plays as Bruno Bucciarati (voice) in Re:ZERO -Starting Life in Another World-.
Yuichi Nakamura is the top #7 member of the cast and appears in 39 episodes.

Chinatsu Akasaki (赤﨑 千夏, Akasaki Chinatsu, August 10, 1987) is a Japanese voice actress affiliated with 81 Produce.

Chinatsu Akasaki plays as Luka Travers (voice) in Re:ZERO -Starting Life in Another World-.
Chinatsu Akasaki is the top #8 member of the cast and appears in 26 episodes.

Yumi Uchiyama (内山 夕実 Uchiyama Yumi, born October 30, 1987) is a Japanese voice actress from Tokyo, Japan and is affiliated with Office Osawa.

Yumi Uchiyama plays as Rudeus Greyrat (voice) in Re:ZERO -Starting Life in Another World-.
Yumi Uchiyama is the top #9 member of the cast and appears in 24 episodes.

Aimi Tanaka (田中 あいみ, Tanaka Aimi, April 28, 1992) is a Japanese voice actress born in Tokyo and raised in Kanagawa Prefecture. She is affliated with 81 Produce.

Aimi Tanaka plays as Yuri (voice) in Re:ZERO -Starting Life in Another World-.
Aimi Tanaka is the top #10 member of the cast and appears in 24 episodes.