Saori Hayami is a Japanese voice actress, singer and narrator. She is represented by the agency I'm Enterprise.] As a singer, she is signed to Warner Bros. Home Entertainment Japan. In 2016, she won the 10th Seiyu Awards for Best Supporting Actress. Her major voice roles include Yukino Yukinoshita in My Teen Romantic Comedy SNAFU, Ayase Aragaki in Oreimo, Shirayuki in Snow White with the Red Hair, Miyuki Shiba in The Irregular at Magic High School, Shinoa Hiiragi in Seraph of the End, Kotohae Hanami in Witchy PreCure!, Urara Shiraishi in Yamada-kun and the Seven Witches, Yotsugi Ononoki in Monogatari, Aila Jyrkiäinen in Gundam Build Fighters, Wako Agemaki in Star Driver, Shōko Nishimiya in A Silent Voice, and Yumeko Jabami in Kakegurui – Compulsive Gambler.

Saori Hayami plays as Haruka Ogasawara (voice) in SPY x FAMILY.
Saori Hayami is the top #1 member of the cast and appears in 26 episodes.

Atsumi Tanezaki (種﨑敦美) is a Japanese voice actress born on September 27. She was formerly affiliated with Toritori Office, but is now represented by Haikyō.

Atsumi Tanezaki plays as Lily (voice) in SPY x FAMILY.
Atsumi Tanezaki is the top #2 member of the cast and appears in 24 episodes.

Takuya Eguchi is a Japanese voice actor and singer from Setagaya, Tokyo. He is affiliated with 81 Produce. He has voiced in a number of lead roles in anime shows including Kazuya Kujo in Gosick, Yoshiharu Sagara in The Ambition of Oda Nobuna, Kon Hokaze in Ixion Saga DT, Hachiman Hikigaya in My Youth Romantic Comedy Is Wrong, As I Expected, William Twining in Devils and Realist, Takeo Gōda in My Love Story. He won Best New Actor award at the 6th Seiyu Awards, and Best Voice Actor in the Newtype Anime Awards 2015. In 2017, Eguchi launched a manga about his life called Eguchi Takuya no Gainen Planet, to be published on Kadokawa's Dengeki Girl's Style Online website.

Takuya Eguchi plays as Shuji Hanma (voice) in SPY x FAMILY.
Takuya Eguchi is the top #3 member of the cast and appears in 24 episodes.

Hiroyuki Yoshino is a Japanese voice actor affiliated with Sigma Seven. He uses the alias Shun Kazama for adult works.

Hiroyuki Yoshino plays as Yaga in SPY x FAMILY.
Hiroyuki Yoshino is the top #4 member of the cast and appears in 21 episodes.

Matsuda Kenichirou is a Japanese voice actor affiliated with Arts Vision.

Kenichirou Matsuda plays as Bardloche Earthwold (voice) in SPY x FAMILY.
Kenichirou Matsuda is the top #5 member of the cast and appears in 12 episodes.

Kazuhiro Yamaji is a Japanese actor and voice actor from Mie Prefecture affiliated with the Seinenza Theater Company.

Kazuhiro Yamaji plays as Henry Henderson (voice) in SPY x FAMILY.
Kazuhiro Yamaji is the top #6 member of the cast and appears in 12 episodes.

Yuhko Kaida plays as Kisharle (voice) in SPY x FAMILY.
Yuhko Kaida is the top #7 member of the cast and appears in 5 episodes.