Justin W. Chambers (born July 11, 1970) is an American actor and former Calvin Klein male fashion model. As of 2005, he is starring in the ABC drama series Grey's Anatomy as Dr. Alex Karev. He is also known for his role in the first season of the CBS crime drama series Cold Case. Description above from the Wikipedia article Justin W. Chambers, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Justin Chambers plays as Alex Karev in Grey's Anatomy.
Justin Chambers is the top #1 member of the cast and appears in 368 episodes.

James Pickens, Jr. (born October 26, 1954) is an American actor. He is best known for his starring role as Dr. Richard Webber on the ABC drama television series Grey's Anatomy, and for his supporting role as Deputy Director Alvin Kersh on later seasons of the Fox Network science fiction series The X-Files. Description above from the Wikipedia article James Pickens, Jr., licensed under CC-BY-SA, full list of contributors on Wikipedia.​

James Pickens Jr. plays as Richard Webber in Grey's Anatomy.
James Pickens Jr. is the top #2 member of the cast and appears in 368 episodes.

Chandra Danette Wilson (born August 27, 1969) is an American actress and director, best known as Dr. Miranda Bailey on the ABC television drama, Grey's Anatomy. Description above from the Wikipedia article Chandra Wilson, licensed under CC-BY-SA, full list of contributors on Wikipedia.​

Chandra Wilson plays as Miranda Bailey in Grey's Anatomy.
Chandra Wilson is the top #3 member of the cast and appears in 368 episodes.

Ellen Kathleen Pompeo is an American actress, known for playing the series protagonist, Meredith Grey, on the ABC medical drama Grey's Anatomy. In 2011, she was named the ninth highest paid television actress, earning $7 million. In 2012, she was named the eighth highest paid television actress, earning $9 million. She has extended her contract for 2 more years which would have her involved with the show until the 10th season.

Ellen Pompeo plays as Meredith Grey in Grey's Anatomy.
Ellen Pompeo is the top #4 member of the cast and appears in 368 episodes.

Kevin McKidd (born 9 August 1973) is a Scottish television and film actor and director. He is known for his prominent television roles, including his performances as Lucius Vorenus in Rome, as Poseidon in Percy Jackson & the Olympians: The Lightning Thief, and as Dr. Owen Hunt in Grey's Anatomy. He has also appeared in films such as Trainspotting, Bedrooms and Hallways, Kingdom of Heaven, The Last Legion, Hannibal Rising, The Acid House, Made of Honor and had the lead role in the cult-classic British horror film Dog Soldiers. McKidd has done voice work and voiced the character of Jezz Torrent, flame haired lead singer of the fictional Scottish hard rock band Love Fist in the video games "Grand Theft Auto: Vice City". He also voiced Captain "Soap" MacTavish in Call of Duty: Modern Warfare 2. Description above from the Wikipedia article Kevin McKidd, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Kevin McKidd plays as Owen Hunt in Grey's Anatomy.
Kevin McKidd is the top #5 member of the cast and appears in 260 episodes.

Jesse Williams plays as Jackson Avery in Grey's Anatomy.
Jesse Williams is the top #6 member of the cast and appears in 212 episodes.

Jessica Capshaw plays as Arizona Robbins in Grey's Anatomy.
Jessica Capshaw is the top #7 member of the cast and appears in 190 episodes.

Sarah Drew is an actress.

Sarah Drew plays as April Kepner in Grey's Anatomy.
Sarah Drew is the top #8 member of the cast and appears in 166 episodes.

Born and raised near London in Berkshire, England, Luddington's love of acting began when she started performing for her family and directing her younger brother at age 5. By 11 she had her first agent and appeared in local theatre productions. While continuing with theatre, she studied in the Theatre Arts program at the prestigious Italia Conti Academy in London, before coming to Hollywood in 2007. Camilla burst into the acting world in the iconic role of Kate Middleton in the Lifetime movie "William and Kate." Airing the week of the Royal Wedding, the ratings were the second highest in Lifetime's history, and the movie proved to be a worldwide success. Luddington portrays another iconic woman, Lara Croft, in the video game "Tomb Raider," produced by Crystal Dynamics. She was praised for giving "Tomb Raider" a much needed reboot. Within 48 hours of the game's release in March of 2013, it sold over 1 million copies. Luddington had a major recurring role opposite David Duchovny and Evan Handler on the critically acclaimed Showtime series, "Californication," in 2012, portraying sweet English nanny Lizzie, an aspiring actress who would do whatever it takes to make it in L.A. In 2012 she also recurred on the award-winning HBO series "True Blood," as Claudette, a fairy who helps protects Sookie (Anna Paquin) and educates her on the world of fairies. Luddington has appeared in various television series, including, "The Defenders," "CSI: Crime Scene Investigation," "The Forgotten," Nickelodeon's "Big Time Rush" and "Days of our Lives." She co-wrote, co-directed and appeared in a short comedy "The Filming of Shakey Willis." Luddington currently resides in Los Angeles.

Camilla Luddington plays as Jo Wilson in Grey's Anatomy.
Camilla Luddington is the top #9 member of the cast and appears in 142 episodes.

Caterina Scorsone (born Caterina Reminy Scorsone on October 16, 1981) is a Canadian actress. She is best known for her role as Amelia Shepherd on Private Practice and for her role as Alice Hamilton in Alice.

Caterina Scorsone plays as Amelia Shepherd in Grey's Anatomy.
Caterina Scorsone is the top #10 member of the cast and appears in 118 episodes.