Michael Austin Cera (born June 7, 1988) is a Canadian actor and musician. He started his career as a child actor, voicing the character of Brother Bear on the children’s television show The Berenstain Bears and portraying a young Chuck Barris in Confessions of a Dangerous Mind (2002). He has had numerous roles in United States television and film productions, including character George Michael Bluth on the sitcom Arrested Development (2003–2006, 2013, 2018–2019) and for his film roles as Evan in Superbad (2007), Paulie Bleeker in Juno (2007), Scott Pilgrim in Scott Pilgrim vs. the World (2010), and a fictional version of himself in This Is the End (2013). He voiced Dick Grayson/Robin in The Lego Batman Movie (2017), Barry (a deformed sausage) in Sausage Party (2016), and Sal Viscuso, the voice behind the announcements in Childrens Hospital. Cera made his Broadway debut in the 2014 production of Kenneth Lonergan's This Is Our Youth. For his performance in the 2018 production of Lonergan's Lobby Hero, Cera was nominated for the Tony Award for Best Performance by a Featured Actor in a Play. Cera starred in the revival of Lonergan's The Waverly Gallery. In addition to acting, Cera is a musician, having released his debut album True That in 2014. Cera has also performed as the touring bassist for indie rock supergroup Mister Heavenly.

Michael Cera plays as John in Life & Beth.
Michael Cera is the top #1 member of the cast and appears in 10 episodes.

American actor and a comedian Michael David Rapaport has acted in more than forty films since the early 1990s. For his television credits he's best known for his roles on the television series Boston Public, Prison Break, Friends, and The War at Home.  Rapaport has appeared in both dramatic and comedic roles on film and television. His movie performances include “Metro”, “Deep Blue Sea”, and “Higher Learning”. Rapaport also had recurring roles on several television shows including: Friends, “The War at Home”, “My Name is Earl” and “Prison Break”. Rapaport is married to Nichole Beattie and they have two children, sons Julian Ali and Maceo Shane.

Michael Rapaport plays as Leonard in Life & Beth.
Michael Rapaport is the top #2 member of the cast and appears in 10 episodes.

Amy Schumer was born in Manhattan and grew up on Long Island, New York. She attended South Side High School and was voted both "Class Clown" and "Teacher's Worst Nightmare" upon graduation in 1999. Schumer graduated from Towson University in 2003 with a degree in theater. She moved to New York City after college, where she studied at the William Esper Studio for two years and worked as a bartender and a waitress. Through her father, she is the niece of Chuck Schumer, U.S. Senator from New York. Amy Schumer portrayed a young woman diagnosed with breast cancer in the off-Broadway black comedy Keeping Abreast. She started doing stand-up comedy on June 1, 2004, when she first performed at Gotham Comedy Club. She recorded a special for Comedy Central before appearing on Last Comic Standing; she said in August 2012 that she thought of the special as her "big break". After not passing an audition for an earlier season, she advanced to the finals of the fifth season of the NBC reality television talent show Last Comic Standing and placed fourth. Schumer said in April 2011, "Last Comic was totally fun. I had a great time because there was no pressure on me; I had been doing stand-up around two years. I wasn't supposed to do well. So every time I advanced it was a happy surprise. I kept it honest on the show and it served me well." (Wikipedia)

Amy Schumer plays as Beth in Life & Beth.
Amy Schumer is the top #3 member of the cast and appears in 10 episodes.

Yamaneika Saunders plays as Maya in Life & Beth.
Yamaneika Saunders is the top #4 member of the cast and appears in 10 episodes.