Although he practices safe sex, Simon panics when his girlfriend of the moment, Sandra (guest-star Olivia Allen), confesses to him that she has an STD. Meanwhile, Martin and Mac (guest-star Kyle Searles) catch Ruthie's boyfriend, Vincent (guest-star Thomas Dekker), on a date with another girl. Also, Matt, Lucy, Kevin and Ruthie have second thoughts about telling Eric and Annie that Mary (Jessica Biel, who does not appear in the episode) is pregnant again, but also to hide the fact that she has deserted her husband Carlos and her baby son Charles. Lastly, Annie decides to go to New York to pay Mary a visit.

The episode was rated 8.20 from 15 votes.

Simon's ex-girlfriend, Georgia (guest-star Rheagan Wallace) tells Simon she's supposedly pregnant and Simon doesn't know how to tell his parents---but Georgia is not being completely honest. Eric, Annie and the twins are on a road trip from Ginger's house back to Glen Oak and reminisce on old times. Meanwhile, Matt rushes Lucy to the hospital when she collapses at the grocery store. They can't track down Kevin as he is working on a drug bust. Lastly, a lonely Ruthie is having a miserable time in Puerto Rico with Mary, Carlos and baby Charles and calls home for comfort.

The episode was rated 8.29 from 17 votes.

When new mom Lucy welcomes guests over to see the baby, Annie immediately becomes concerned, believing that Lucy doesn't fully understand the health risks of exposing a newborn to strangers. Lucy's determination to show everyone that she has parenting under control leaves Kevin to question his role as a father, especially when they're alone. Also, struggling new parents Kevin and Lucy move back into the Camden home, while Martin moves into the garage apartment. Eric is worried that he and Annie are doing too much in helping Kevin and Lucy adjusting to parenthood as they're taking on more than they should as grandparents. Meanwhile, Martin's classmate Zoe (guest-star Katie Cassidy) intentionally falls asleep on the couch of his apartment so that she can tell everyone at school that they slept together. When Ruthie finds out about Martin's overnight guest she sees it as the perfect opportunity to blackmail him into getting her a date with her crush, Vincent (guest-star Thomas Dekker).

The episode was rated 8.33 from 15 votes.

Ruthie is on cloud nine when an emotional Eric and Annie reluctantly agree to let her go on her first official date. However, Ruthie isn't surprised to find the family handling her big news with their usual crazy Camden ways: Annie and Lucy decide it's their job to help Ruthie prepare for her date with Vincent (guest star Thomas Dekker); Kevin takes it upon himself to give Ruthie "the talk"; Sam and David change into their Sunday best so they can go on the date as well; an overprotective Martin and Mac (guest star Kyle Searles) decide to spy on Ruthie and Vincent's date; and Matt volunteers to play chaperone, but finds himself in a web of lies to protect Ruthie's feelings.

The episode was rated 8.36 from 14 votes.

With Thanksgiving just two weeks away, Eric and the kids notice that Annie is acting strangely, especially after she learns that Matt and Sarah (guest-star Sarah Danielle Madison) won't be able to spend the holidays in Glenoak. In fact, the majority of the family has made plans of their own and Eric worries how Annie will take the news. Mary (Jessica Biel does not appear in this episode) and Carlos (guest-star Carlos Ponce) decide to spend the holiday in Puerto Rico with Carlos' family and invite Ruthie to join them. Meanwhile, Simon, who has something to tell his parents, but can't get up the nerve. Instead he decides to stay at school for work. Also, Martin has plans to go camping with Mac (guest-star Kyle Searles). Lastly, a strong-willed and pregnant Lucy is determined to do the cooking and decorating this year.

The episode was rated 8.40 from 15 votes.

Although she is worried about the lesson plan for the class she is teaching on abstinence, Lucy is excited when Eric tells her she is now the Associate Pastor and will soon give her first sermon. Meanwhile, during Simon's visits with Dr. Gibson (guest-star David Piel), he confesses that he has been using his relationship with Georgia (guest-star Rheagan Wallace) to block out the guilt he still feels about the fatal traffic accident. Lastly, Ruthie falls for a guy she meets in detention, Harry (guest-star Aaron Carter), a foster kid currently living in a county facility, despite Martin's reservations.

The episode was rated 8.42 from 12 votes.

Simon is reluctant to talk to Eric and Annie about his relationship with Georgia (guest star Rheagan Wallace). However, he eventually drops the bomb that they are having sex and that he's currently on academic probation for skipping classes to be with her. Meanwhile, Simon's situation helps Eric realize that the church should teach teens the importance of abstinence and he asks Lucy to lead a class on the subject. Also, Lucy and Kevin learn the sex of their baby, and Lucy starts to question her ability to be a good mother. Matt is worried that Martin is still broken-hearted over Cecilia and will tell her about Simon's new relationship with Georgia. Lastly, Matt chips away at Ruthie's unwillingness to apologize to Martin.

The episode was rated 8.43 from 14 votes.

Kevin learns that Simon has been kicked out of his dorm for allowing a school friend, Christina (guest-star Lauren Storm), to stay with him. When Eric comes to the rescue, he learns that Christina is a product of social services and has three younger siblings separated from each other and all in need of homes. Eric realizes that their situation may be more than he can handle alone, and with the help of Annie, encourages the congregation to make a difference by becoming licensed foster parents.

The episode was rated 8.46 from 13 votes.

When Simon asks Matt to prescribe birth control pills for his current girlfriend, a false rumor spreads through the house that she is pregnant. Meanwhile, Lucy and Kevin have to decide whether to sell their new house back to its previous owners, Eric and Annie are upset that Kevin has been keeping a gun in the house for protection. Lastly, the Camden kids attempt to hide a big secret about Mary (Jessica Biel, who does not appear in the episode) from their parents.

The episode was rated 8.50 from 12 votes.

Eric seeks help from Mary's (Jessica Biel, who does not appear in the episode) ex-boyfriend, Wilson (guest-star Andrew Keegan) after Charlie (guest-star Eric Panler), a new father, confesses to Eric that he has made a mistake and can't handle the responsibility of being a young dad. Meanwhile, Lucy and Kevin argue over which doctor they prefer, and Ben (guest-star Geoff Stults), who has taken an unusual interest in their pregnancy, only makes matters worse by siding with Lucy; and Ruthie has hidden intentions for wanting to hang out with Martin and his best friend Mac (guest-star Kyle Searles), which only leads to disappointment since Mac thinks of her more as a little sister.

The episode was rated 8.54 from 13 votes.

As election day approcahes, Ruthie is on a mission to develop her own opinions about politics after seeing how much Martin knows about world politics. Meanwhile, both Eric and Annie are suspicious that the other did not vote in the last election. Also, Lucy is feeling the pressure of registering to vote and is surprised to learn that Kevin hasn't changed his address and therefore isn't registered either. Eric is having a hard time teaching the twins that politics are not stupid. Lastly, the family gets a nice call from Carlos and baby Charles.

The episode was rated 8.60 from 10 votes.

After being taunted for wearing second-hand clothes at "Second Hand Rose" by Vincent's (guest-star Thomas Dekker) new girlfriend, Margot (guest-star Ashley Benson), a distraught Ruthie runs into the bathroom and finds Martin's girlfriend, Zoe (guest-star Katie Cassidy), recovering from a fainting spell as two girls try to help her. Zoe confides that her family doesn't have enough money for food and makes Ruthie promise not to tell anyone. However, when Martin breaks up with Zoe because he doesn't like her conceited attitude, Zoe thinks Ruthie has betrayed her confidence. Meanwhile, Kevin unsuccessfully tries to create some alone time with Lucy, but is frustrated with Lucy's obsession over Savannah. Also, Eric and Annie suspect that Sam and David are feigning being sick so they can stay up late and eat sweets. Lastly, Sam is jealous of the attention being given to an ill David.

The episode was rated 8.65 from 17 votes.

When Kevin leads Venus (guest-star Martha Plimpton), a young woman, to believe that Martin is a rookie cop, she quickly expresses interest in him. Martin's friend Mac (guest-star Kyle Searles) encourages him to pursue Venus. Martin has a hard time revealing the truth after he learns that Venus' father is serving in the Middle East. Meanwhile, Eric and Annie are worried that Martin is getting in over his head with Venus and enlist Kevin to fix things, which only leads to rumors around the police station that Kevin is cheating on Lucy. Mac also jumps in by spreading rumors about Martin at school. Lastly, Ben (guest-star Geoff Stults) continues to hide his relationship with Lucy's new baby doctor, even though they spend a weekend together.

The episode was rated 8.69 from 16 votes.

An extremely nervous Simon comes home to Glenoak to await the results of his STD test. Eric counsels a woman (guest-star Erika Alexander) who is caring for her two daughters (guest-stars Bree' Anna Banks and Brandi Vanice) with sickle cell anemia and whose absentee father (guest-star Victor Love) is hoping to take them back with him to Memphis for treatment at St. Jude Children's Research Hospital. Meanwhile, Ruthie's ex-boyfriend, Peter (guest-star Scotty Leavenworth), pays her a surprise visit, which creates problems with her current boyfriend, Vincent (guest-star Thomas Dekker). Lucy and Kevin disagree over who should care for Savannah when Lucy returns to work. Lastly, Martin misses an important call from his father in Iraq while sneaking out of the house to be with his girlfriend.

The episode was rated 8.75 from 12 votes.

Eric is approached by a young pregnant girl, Leanne (guest-star Amanda Fuller), for help in finding a family to adopt her baby. However, when Leanne goes into labor, she has a change of heart and suddenly Eric and Annie are stuck with the task of trying to convince Leanne's mother to support her and help find the baby's father. Meanwhile, Simon runs into the brother of the young boy he accidentally killed in the car accident, only to find that the brother has forgiven Simon and would like to help him find closure. Also, Harry (guest-star Aaron Carter) is confronted by Kevin and Martin for wanting to break up with Ruthie, and all three are surprised to learn that Ruthie wants the exact same thing; and Lucy teaches her first sex education class and finds she may be better at it than she expected.

The episode was rated 8.75 from 16 votes.