Grey's Anatomy

10 Best Episodes of Grey's Anatomy - Season 4

Grey's Anatomy has been a fan favorite since its debut in 2005. The show follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital, delivering drama, romance, and heartbreak in equal measure. With 22 seasons under its belt, the show has had its fair share of standout moments and fan-favorite episodes.

To celebrate the show's success, we've compiled a list of the best episodes ranked by viewers. From shocking twists to heartwarming moments, these episodes are sure to leave you on the edge of your seat. Whether you're a long-time fan or a newcomer to the series, these episodes are a must-watch for any Grey's Anatomy enthusiast.

So sit back, grab some popcorn, and get ready to relive some of the most iconic moments from Grey's Anatomy. With its gripping storylines, talented cast, and unforgettable characters, it's no wonder the show has remained a staple of primetime TV for over 15 years.

Written by Sophie and last updated on may 04, 2024.

PS: The following content contains spoilers!

PPS: I will admit that parts of this page was written with the help of AI - it makes my work so much easier to not start from a blank page!

Advertisement
Grey's Anatomy - S4E8

#15 - Forever Young (Season 4 - Episode 8)

There has been a bus crash and the patients are in the ER. Meredith and Derek's relationship gets more complicated when he dates a fellow doctor. Meredith's dad goes to visit her at the hospital.

The episode was rated 7.70 from 647 votes.

Grey's Anatomy - S4E1

#14 - A Change Is Gonna Come (Season 4 - Episode 1)

Advertisement

Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Another two new interns will be introduced in this season premiere. And they'll have their hands full when a three-car accident sends multiple casualties pouring into Seattle Grace. Some of the doctors need to deal with new stressed out interns. A young boy brings his bleeding deer to the hospital in the hope a doctor will save her.

The episode was rated 7.70 from 742 votes.

Grey's Anatomy - S4E7

#13 - Physical Attraction, Chemical Reaction (Season 4 - Episode 7)

Izzie and George's new-founded relationship results in them having bad sex. Callie's Chief Resident position is taken away from her, and Bailey is the humble replacement. Meredith can barely handle it with Lexie anymore.

The episode was rated 7.71 from 661 votes.

Grey's Anatomy - S4E12

#12 - Where The Wild Things Are (Season 4 - Episode 12)

Advertisement

Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating and Meredith has noticed the activities of her current off-again ex-boyfriend. The doctor's are in the midst of a competition.

The episode was rated 7.71 from 648 votes.

Grey's Anatomy - S4E2

#11 - Love/Addiction (Season 4 - Episode 2)

A patient is in the hospital because they fell asleep in a hazardous situation. A patient's home laboratory blew up in an apartment building and the victims flood the hospital. Alex investigates the cause of the incident by talking to a really old guy who lived in the building. Jane Burke shows up to deal with what her son left behind. Lexie tries to talk to Meredith. Callie is overwhelmed by her new position while Bailey is searching for things to do.

The episode was rated 7.73 from 710 votes.

Grey's Anatomy - S4E6

#10 - Kung Fu Fighting (Season 4 - Episode 6)

Advertisement

A patient comes to the ER with a dream and a condition which may prevent him form realizing it. Two patients are competing to win something big. One of them convinces an intern to take their place.

The episode was rated 7.76 from 674 votes.

Grey's Anatomy - S4E5

#9 - Haunt You Every Day (Season 4 - Episode 5)

It's Halloween at Seattle Grace! There may be jokes, pranks, and/or scare tactics. Some of the women form a club based on an experience they all share. A man volunteers for what most of the doctors believe is an unnecessary surgery. One of the patients is in the hospital because they tried to carve a pumpkin in an unconventional manner.

The episode was rated 7.76 from 668 votes.

Grey's Anatomy - S4E14

#8 - The Becoming (Season 4 - Episode 14)

Advertisement

The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn't enough to stop one woman from spending time with him. Christina is affected by Burke's career developments.

The episode was rated 7.76 from 629 votes.

Grey's Anatomy - S4E3

#7 - Let the Truth Sting (Season 4 - Episode 3)

The doctors meet the world's oldest intern. Marcy brings in her son Henry because she finds his change in behavior suspicious. A patient named Connie may lose her vocal chords unless Mark and Richard can perform a radical new surgery. George impresses the other interns at work but at home he is trying to deal with his guilt about having sex with Izzie.

The episode was rated 7.77 from 665 votes.

Grey's Anatomy - S4E13

#6 - Piece of My Heart (Season 4 - Episode 13)

Advertisement

Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek's clinical trial experiences one or two developments.

The episode was rated 7.80 from 635 votes.

Grey's Anatomy - S4E4

#5 - The Heart of the Matter (Season 4 - Episode 4)

A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen soccer player needs counseling because of his father and surgery for an injury he sustained while playing the game. Another patient's, named Courtney, finds out that her cancer is back.

The episode was rated 7.83 from 677 votes.

Grey's Anatomy - S4E9

#4 - Crash Into Me (1) (Season 4 - Episode 9)

Advertisement

An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava returns for Alex and meets his other girlfriend in the process.

The episode was rated 7.85 from 666 votes.

Grey's Anatomy - S4E10

#3 - Crash Into Me (2) (Season 4 - Episode 10)

Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to save a patient; Bailey struggles to balance her personal life with her work.

The episode was rated 7.89 from 656 votes.

Grey's Anatomy - S4E16

#2 - Freedom (1) (Season 4 - Episode 16)

Advertisement

A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

The episode was rated 8.00 from 652 votes.

Grey's Anatomy - S4E17

#1 - Freedom (2) (Season 4 - Episode 17)

In the latest episode of Grey's Anatomy, titled "Freedom (2)", a couple takes a leap of faith as they undergo a life-changing surgery. Meanwhile, Derek and Meredith's clinical trial receives a glimmer of hope when a new patient decides to join their groundbreaking research. And amidst the chaos, Izzie steps up to lend a helping hand to Alex. Will this unexpected act of kindness reignite their complicated relationship?

But that's not all – things heat up in the romance department as McSteamy finds himself entangled with someone new. Will this steamy affair lead to a lasting connection or just another fleeting encounter?

As emotions run high and relationships become even more tangled, viewers can't help but share their thoughts. Some are tired of Alex's behavior and are hoping for a drastic change, while others are overjoyed to see Meredith and Derek finally finding their way back to each other. But amidst all the drama, one burning question remains: where did all those candles come from? Stay tuned to find out!

The episode was rated 8.21 from 584 votes.

Search for TV shows...

About Series with Sophie

Welcome to our community!

We are a community of women who are passionate about our favorite series and want to share that passion with others.

Our mission is to create a space where women can discover new content, connect with like-minded individuals, and engage in meaningful discussions about the series we love.

We believe that everyone should have access to reliable and trustworthy information about their favorite shows, and we strive to be the premier destination for women seeking that information. Whether you're looking for recaps, fan theories, or just want to connect with other fans, we've got you covered.

So join us and be a part of our growing community of series enthusiasts!